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    Improving patient care through objective detection and monitoring for acute encephalopathy and delirium

    DeltaScan revolutionises patient care

    The development of DeltaScan was initiated by clinicians with the aim to improve patient recovery by detecting acute encephalopathy and delirium more often and earlier. Better recognition is beneficial not only for patients and their relatives, but also for clinicians and budget holders. Guidelines prescribe that patients with an increased risk of delirium should be monitored at least once per shift.

    We developed Prolira-DeltaScan to detect acute encephalopathy and delirium more frequently and earlier. Our goal is to improve the quality of care, as better detection of delirium leads to better patient outcomes, shorter hospital stays and a reduction in healthcare costs. DeltaScan is an objective medical device that works on the basis of 1-channel EEG signal (Electroencephalography). EEG has proven to be a biomarker for delirium (Source: Van der Kooi et al., 2015, Chest) and acute encephalopathy (Source: Hut et al., 2021, Psychiatry Clin Neurosci.). The result (Score) of DeltaScan is a parameter for acute encephalopathy and delirium.

    The 1-channel EEG, made by DeltaScan, clearly shows a difference between a patients with delirium and patient without delirium (Source: Van der Kooi et al., 2015, Chest). Delirium is characterized by strong and strongly slowed waves in an EEG (Source: Van der Kooi et al., 2015, Chest / Kimchi et al., 2019, Neurology).

    These waves are called polymorphic Delta waves (Figure 1). When there is no delirium, these waves don’t present themselves (Figure 2).

    Medical device based on EEG

    EEG (ElectroEncephaloGram) is the depiction of the electrical activity in the brain. As acute encephalopathy and delirium are forms of acute failure of the brain, DeltaScan is a practical device for detection & monitoring for delirium and acute encephalopathy in patients. DeltaScan can be used by healthcare professionals (nurses and doctors) at the patient’s bedside. The patient’s brain activity is rapidly measured and DeltaScan detects and quantifies those specific waveshape patterns in the EEG, that are characteristic for acute encephalopathy and delirium (also called polymophic Delta waves, PMD).

    EEG without delirium

    EEG with delirium

    Are you interested, or do you have any questions?

    Please contact us!


      We offer 3 free e-learning modules, each of about 10 minutes, that
      are informative and interactive, partly because they contain videos: 

      1. for nurses: delirium and acute encephalopathy
      2. for doctors: delirium
      3. for healthcare professionals: Prolira-DeltaScan use

      or contact our Account Managers

      Delirium detection and monitoring

      Compared to current subjective screening methods for delirium, DeltaScan aims to improve the “patient journey” of patients at risk of delirium.

      How to use DeltaScan

      This short video explains how to use DeltaScan.

      Are you interested, or do you have any questions?

      Please contact us!

        DeltaScan® is an EU registered trademark (Certificate Nr 018280613)

        Prolira BV
        IJsselburcht 3
        6825 BS Arnhem
        The Netherlands

        Visiting address:
        Padualaan 8
        3584 CH Utrecht
        The Netherlands


        +31 (0)85 060 1656