New Validation Study

A major milestone for improving brain health for hospitalized seniors. This important study validates the accuracy of using the DeltaScan monitor to assess the brain state in hospitalized seniors. Cognitive decline and delirium is an all too common post-operative outcome for patients over 65 that lead to serious short- and long-term complications. This is a great step toward better care through early detection of this elusive problem.

Published in The American Journal of Geriatric Psychiatry

DeltaScan for the Assessment of Acute Encephalopathy and Delirium in ICU and non-ICU Patients, a Prospective Cross-Sectional Multicenter Validation Study

Fienke L. Ditzel, M.D. • Suzanne C.A. Hut, Ph.D. • Mark van den Boogaard, R.N., Ph.D. • Michel Boonstra, M.Sc. • Frans S.S. Leijten, M.D., Ph.D. • Evert-Jan Wils, M.D., Ph.D. • Tim van Nesselrooij • Marjan Kromkamp, M.D., Ph.D. • Paul J.T. Rood, R.N., Ph.D. • Christian Röder, M.D., Ph.D. • Paul F. Bouvy, M.D., Ph.D. • Michiel Coesmans, M.D., Ph.D. • Robert Jan Osse, M.D., Ph.D. • Monica Pop-Purceleanu, M.D., Ph.D. • Edwin van Dellen, M.D., Ph.D. • Jaap W.M. Krulder, M.D., Ph.D. • Koen Milisen, RN, Ph.D. • Richard Faaij, M.D., Ph.D. • Ariël M. Vondeling, M.D. • Ad M. Kamper, M.D., Ph.D. • Barbara C. van Munster, M.D., Ph.D. • Annemarieke de Jonghe, M.D. • Marian A.M. Winters, Ph.D. • Jeanette van der Ploeg • Sanneke van der Zwaag, M.Sc. • Dineke H.L. Koek, M.D., Ph.D. • Clara A.C. Drenth-van Maanen, M.D. • Albertus Beishuizen, M.D., Ph.D. • Deirdre M. van den Bos, M.D. • Wiepke Cahn, M.D., Ph.D. • Ewoud Schuit, Ph.D. • Arjen J.C. Slooter, M.D., Ph.D.

DOI: https://doi.org/10.1016/j.jagp.2023.12.005

Highlights

• What is the primary question addressed by this study?
  What is the accuracy of DeltaScan; a portable brain state monitor that offers real-time automated artifact rejection and analysis, delivering a probability score for both acute encephalopathy and delirium in both ICU and non-ICU patients?
• What is the main finding of this study?
  The device can detect acute encephalopathy and delirium with good discrimination statistics especially in older patients, regardless of their postoperative state, psycho-active medication use, or prior psychiatric history.
• What is the meaning of the finding?
  The study suggests that the DeltaScan could be a valuable tool for improving delirium monitoring practices, given that delirium is often overlooked, difficult to differentiate from other psychiatric disorders, and current questionnaire-based monitoring tools suffer from inter-rater variability.

Full article can be found here: https://www.ajgponline.org/article/S1064-7481(23)00499-2/fulltext