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2024 CLARITY Program     continue reading →

DeltaScan

Clinical Study Data

Clinical Benefit Studies

Cardiac Surgery

Patients
903
Patients
mst-delirium-qi-program

By using DeltaScan as part of a delirium QI program, MST showed a length of stay reduction of 1 day (from 6 to 5 days average LOS) for the total population (p=0.008).

As presented during webinar on February 21, 2024

Cardiac Surgery

Patients
850
Patients
hdz-delirium-management-improvement

By implementing a delirium reduction program, including DeltaScan, delirium incidence was reduced from 25% to 8%. Resulting in a cost savings of several million euros.

As presented during webinar on February 21, 2024

Hematology/Oncology

Patients
20
Patients
car-t-neurotoxicity-2

CAR T-cell therapy has a up to 50% incidence of serious neurotoxicity complications. In a pilot study DeltaScan detected the condition 12-24 hrs earlier then the standard approach.

Tienstra et al., 2024

Validation Studies

Proof of concept study

Patients
56
Patients
Technical Proof Study Prolira Deltascan

Demonstrates that the relative deltapower from a one minute artefact free EEG recording, with only two electrodes in a frontal-parietal derivation can distinguish among patients who have delirium and those who do not.

Kooi et al., 2015, Chest

Validation study

Patients
145
Patients

321 EEGs

Validation Study EEG Acute Encephalopathy

Demonstrates that automated polymorphic delta activity detection in 1-channel EEG [ed.: DeltaScan algorithm] has a diagnostic performance for acute encephalopathy >85% (AUROC=0.86, CI = [0.81–0.90]). 

Ditzel et al., 2022, PCN

Multi-center study

Patients
434
Patients
Clearance Study EEG Acute Encephalopathy DeltaScan

Demonstrates the diagnostic performance of DeltaScan is >85% for acute encephalopathy (AUROC=0.855, CI = [0.82, 0.89]) on ICUs and ward patients. The majority of data is from patients 60 years or older.

Ditzel et al., 2023, AMGP

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